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Pokey Mans is Challenge #33. You start with Friendly Ball and Mom's Eyeshadow with the objective being to kill Isaac.
Some spawns from the Friendly Ball can cause unavoidable damage in certain rooms. Hazards or enemies can be hidden by larger allies or if many are in a group.
- The Friendly Ball works differently in this challenge, summoning a random charmed enemy with each use, without the need to catch any.
- As soon as a charmed friend dies, the Friendly Ball instantly recharges and should be used multiple times per room.
- Any monster designed to spawn monsters will have the spawned monster friendly towards Isaac and count towards recharging the Friendly Ball. Example: The spider nub spawns friendly spiders.
- However, monsters that explode into other monsters will not have their replacements friendly.
- Some monsters will die as soon as they are spawned, leaving behind unfriendly replacements.
- Do not leave a room before the Friendly Ball has spawned its monster. Your charges will be consumed and no monster will die to replenish the charges. You will have to gain charges the old fashioned way.
- While your own bombs won't damage the spawned monster, certain items (like Contagion) will.
- The title of the challenge is a play on the word Pokémon.