The Host

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The Host is Challenge #18, starting with the items Spider Baby, The Mulligan, and The Tick trinket. The goal is to defeat Mom. This Challenge is unlocked by default.

Difficulty[modifier | modifier le wikicode]

Strategy[modifier | modifier le wikicode]

  • Shops can sell Mom's Purse, which will allow a second trinket.
  • Shops can also sell Hive Mind, which will make flies and spiders bigger and stronger.

Reward[modifier | modifier le wikicode]

Completing this challenge unlocks Tech.5, which randomly shoots lasers when Isaac fires.

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