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Trisagion Icon.png
Item altar.png
Texte original "Smite thy enemy"
Traduction française ""
Salle de l'Ange
Dlc a† Indicator.png

Trisagion is a passive item added in Booster Pack #4.


  • Tears are replaced with piercing white blasts of light.
    • Blasts deal 33% of regular tear damage, but can hit the same enemy multiple times.
    • Blasts do not knock back enemies.


  • Brimstone: Overrides Trisagion.
  • Dr. Fetus: Overrides Trisagion.
  • Epic Fetus: Overrides Trisagion.
  • Haemolacria: Functions otherwise as normal, but all blasts deal the same reduced damage.
  • Ipecac: Ipecac's damage boost applies; the light beam causes invisible explosions dealing full damage when it impacts something or runs out of range, making it unpredictable and dangerous to use.
  • Lachryphagy: The blasts will slow down and float like Lachryphagy tears and eventually burst, but can not consume each other.
  • A Lump of Coal: No effect, the blasts' damage is unchanged.
  • Mom's Knife: Overrides Trisagion.
  • Pop!: The blasts will slow down and float like Pop! tears, but will not bounce off each other.
  • Tech X: Overrides Trisagion.
  • Technology: Overrides Trisagion.


  • Bloodshot Eye: The tears fired from the Bloodshot Eye are replaced with Trisagion tears, even if Trisagion is already overridden by something like Brimstone.
  • Godhead: Although the damaging aura isn't visible, it still exists and is not affected by Trisagion's damage reduction.
  • Homing tears: The blasts can deal extra damage as they remain in contact with enemies longer.
  • The Ludovico Technique: The beam becomes controllable, still dealing reduced damage but at very high rate.
  • Proptosis: Base damage is doubled and beam damage is boosted to about 65%. Blasts lose very little power as they travel further.
  • Rubber Cement: The blasts still pierce enemies, but bounce off obstacles and walls.

In-game Footage


  • Trisagion is based on this Steam Workshop item by x Wyvern x.
  • The name is a reference to one of the oldest christian hymns.